DegronMD - Q9H467(CUEDC2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R91S	TCGA-GV-A6ZA	BLCA	TCGA	NKENL	DEG_APCC_KENBOX_2	92:96	Mutation rewiring degron network	0.3056
p.R91S	DO49776	BLCA	ICGC	NKENL	DEG_APCC_KENBOX_2	92:96	Mutation rewiring degron network	0.3056
p.P98L	TCGA-WE-AAA0	SKCM	TCGA	NKENL	DEG_APCC_KENBOX_2	92:96	Mutation rewiring degron network	0.2778
p.P98L	DO51294	SKCM	ICGC	NKENL	DEG_APCC_KENBOX_2	92:96	Mutation rewiring degron network	0.2778
p.P98S	TCGA-WE-AAA0	SKCM	TCGA	NKENL	DEG_APCC_KENBOX_2	92:96	Mutation rewiring degron network	0.2778
p.P98S	DO51294	SKCM	ICGC	NKENL	DEG_APCC_KENBOX_2	92:96	Mutation rewiring degron network	0.2778
p.P98Q	DO229032	LICA	ICGC	NKENL	DEG_APCC_KENBOX_2	92:96	Mutation rewiring degron network	0.2778
p.N95K	DO27891	ORCA	ICGC	NKENL	DEG_APCC_KENBOX_2	92:96	Mutation altering degron motif	0.6918
p.D89N	SIDM00506	Small Cell Lung Carcinoma	GDSC	NKENL	DEG_APCC_KENBOX_2	92:96	Mutation rewiring degron network	0.25
p.D89N	ACH-000508	Lung Cancer	CCLE	NKENL	DEG_APCC_KENBOX_2	92:96	Mutation rewiring degron network	0.25
p.D89N	ACH-000975	Lung Cancer	CCLE	NKENL	DEG_APCC_KENBOX_2	92:96	Mutation rewiring degron network	0.25
p.D89N	COR-L88	lung	COSMIC	NKENL	DEG_APCC_KENBOX_2	92:96	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons