DegronMD - Q9H4D5(NXF3)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S515P	TCGA-77-A5G1	LUSC	TCGA	AFSSS	DEG_SPOP_SBC_1	513:517	Mutation altering degron motif	0.6752
p.L509I	TCGA-86-8585	LUAD	TCGA	AFSSS	DEG_SPOP_SBC_1	513:517	Mutation rewiring degron network	0.2222
p.V518M	TCGA-A6-A567	COAD	TCGA	AFSSS	DEG_SPOP_SBC_1	513:517	Mutation rewiring degron network	0.3056
p.S504N	TCGA-CN-5356	HNSC	TCGA	AFSSS	DEG_SPOP_SBC_1	513:517	Mutation rewiring degron network	0.0833
p.S522F	ACH-001552	Skin Cancer	CCLE	AFSSS	DEG_SPOP_SBC_1	513:517	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons