DegronMD - Q9H5I5(PIEZO2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.H1839Y	DO222576	COCA	ICGC	PPSY	ITCH	1828:1831	Mutation rewiring degron network	0.1111
p.V1835G	DO234422	ESAD	ICGC	PPSY	ITCH	1828:1831	Mutation rewiring degron network	0.2222
p.T1820N	DO228948	LICA	ICGC	LTPEEE	DEG_SCF_FBW7_2	1809:1814	Mutation rewiring degron network	0.1667
p.T1820N	DO228948	LICA	ICGC	PPSY	ITCH	1828:1831	Mutation rewiring degron network	0.1111
p.D1822E	DO229029	LICA	ICGC	LTPEEE	DEG_SCF_FBW7_2	1809:1814	Mutation rewiring degron network	0.1111
p.D1822E	DO229029	LICA	ICGC	PPSY	ITCH	1828:1831	Mutation rewiring degron network	0.1667
p.A1801D	DO229009	LICA	ICGC	LTPEEE	DEG_SCF_FBW7_2	1809:1814	Mutation rewiring degron network	0.1111
p.D1824N	DO222908	MELA	ICGC	LTPEEE	DEG_SCF_FBW7_2	1809:1814	Mutation rewiring degron network	0.0556
p.D1824N	DO222908	MELA	ICGC	PPSY	ITCH	1828:1831	Mutation rewiring degron network	0.2222
p.L1815V	DO233366	RECA	ICGC	LTPEEE	DEG_SCF_FBW7_2	1809:1814	Mutation rewiring degron network	0.3056
p.G1823R	DO43210	UCEC	ICGC	LTPEEE	DEG_SCF_FBW7_2	1809:1814	Mutation rewiring degron network	0.0833
p.G1823R	DO43210	UCEC	ICGC	PPSY	ITCH	1828:1831	Mutation rewiring degron network	0.1944
p.V1799L	ACH-000088	Non-Cancerous	CCLE	LTPEEE	DEG_SCF_FBW7_2	1809:1814	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons