DegronMD - Q9H6J7(CSTPP1)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q204K	TCGA-85-6561	LUSC	TCGA	DRHKYSCPP	CBL_PTK	211:219	Mutation rewiring degron network	0.1389
p.Q204K	DO26518	LUSC	ICGC	DRHKYSCPP	CBL_PTK	211:219	Mutation rewiring degron network	0.1389
p.R212L	TCGA-ER-A19B	SKCM	TCGA	DRHKYSCPP	CBL_PTK	211:219	Mutation altering degron motif	0.7316
p.R212L	DO47491	SKCM	ICGC	DRHKYSCPP	CBL_PTK	211:219	Mutation altering degron motif	0.7316
p.S228N	DO227969	COCA	ICGC	DRHKYSCPP	CBL_PTK	211:219	Mutation blocking phosphorylation signal	0.5278
p.F202L	DO231086	LUSC	ICGC	DRHKYSCPP	CBL_PTK	211:219	Mutation rewiring degron network	0.0833
p.R212W	DO232224	PBCA	ICGC	DRHKYSCPP	CBL_PTK	211:219	Mutation altering degron motif	0.7523

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons