DegronMD - Q9H6S1(AZI2)

AZI2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.F278V	TCGA-CA-6717	COAD	TCGA	NFTATYTRHP	CBL_PTK	277:286	Mutation altering degron motif	0.5957
p.F278V	DO8264	COAD	ICGC	NFTATYTRHP	CBL_PTK	277:286	Mutation altering degron motif	0.5957
p.F278V	SIDM00118	Colorectal Carcinoma	GDSC	NFTATYTRHP	CBL_PTK	277:286	Mutation altering degron motif	0.5957
p.F278V	ACH-001081	Colon/Colorectal Cancer	CCLE	NFTATYTRHP	CBL_PTK	277:286	Mutation altering degron motif	0.5957
p.F278V	HCC2998	large intestine	COSMIC	NFTATYTRHP	CBL_PTK	277:286	Mutation altering degron motif	0.5957
p.F278L	DO222798	COCA	ICGC	NFTATYTRHP	CBL_PTK	277:286	Mutation altering degron motif	0.587
p.S270R	DO229026	LICA	ICGC	NFTATYTRHP	CBL_PTK	277:286	Mutation blocking phosphorylation signal	0.5833
p.S270R	DO229032	LICA	ICGC	NFTATYTRHP	CBL_PTK	277:286	Mutation blocking phosphorylation signal	0.5833
p.P286S	DO220885	MELA	ICGC	NFTATYTRHP	CBL_PTK	277:286	Mutation altering degron motif	0.6752
p.L288F	ACH-000868	Lung Cancer	CCLE	NFTATYTRHP	CBL_PTK	277:286	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc