DegronMD - Q9H6U6(BCAS3)

BCAS3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L382P	TCGA-FI-A2F4	UCEC	TCGA	PWSSS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.25
p.M382I	DO44027	BLCA	ICGC	PWSSS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.25
p.E380K	DO219038	BLCA	ICGC	PWSSS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.1944
p.I394L	DO45317	LUAD	ICGC	PWSSS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.1944
p.A391T	DO24692	LUAD	ICGC	PWSSS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.2778
p.L388R	DO27871	ORCA	ICGC	PWSSS	DEG_SPOP_SBC_1	385:389	Mutation altering degron motif	0.8428
p.D397G	DO42023	UCEC	ICGC	PWSSS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.1111
p.D397N	DO43755	UCEC	ICGC	PWSSS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.1111
p.H377Y	SIDM01039	Other Solid Cancers	GDSC	PWSSS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.1111
p.H377Y	ACH-001529	Endometrial/Uterine Cancer	CCLE	PWSSS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.1111
p.H377Y	JAR	placenta	COSMIC	PWSSS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.1111
p.V393I	SIDM00282	Colorectal Carcinoma	GDSC	PWSSS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.2222
p.V393I	ACH-000998	Colon/Colorectal Cancer	CCLE	PWSSS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.2222
p.V393I	CW-2	large intestine	COSMIC	PWSSS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc