DegronMD - Q9H6W3(RIOX1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S48F	SIDM00194	Colorectal Carcinoma	GDSC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation blocking phosphorylation signal	0.75
p.S48F	SNU-61	large intestine	COSMIC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation blocking phosphorylation signal	0.75
p.L32M	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.L32M	SIDM00969	Ovarian Carcinoma	GDSC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.L32M	SIDM00656	Burkitt's Lymphoma	GDSC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.L32M	SIDM00741	Small Cell Lung Carcinoma	GDSC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.L32M	SIDM00751	Non-Small Cell Lung Carcinoma	GDSC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.L32M	SIDM00694	Other Solid Cancers	GDSC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.L32M	SIDM00254	Neuroblastoma	GDSC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.L32M	SIDM00844	Burkitt's Lymphoma	GDSC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.L32M	SIDM00256	Neuroblastoma	GDSC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.L32M	SIDM00760	Small Cell Lung Carcinoma	GDSC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.L32M	SIDM00641	Burkitt's Lymphoma	GDSC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.L32M	SIDM01686	Chronic Myelogenous Leukemia	GDSC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.R54S	SIDM00457	Plasma Cell Myeloma	GDSC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389
p.R54S	OPM-2	haematopoietic and lymphoid tissue	COSMIC	IRKQLRSVV	DEG_APCC_DBOX_1	39:47	Mutation rewiring degron network	0.1389

Kaplan plot for RIOX1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RIOX1

UniProt ID: Q9H6W3

Entrez ID: 79697

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for RIOX1 in