DegronMD - Q9H7F4(TMEM185B)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P320T	TCGA-FI-A2D5	UCEC	TCGA	IAPIFGKKARVVI	DEG_ODPH_VHL_1	318:330	Mutation altering degron motif	0.7031
p.P320T	DO41331	UCEC	ICGC	IAPIFGKKARVVI	DEG_ODPH_VHL_1	318:330	Mutation altering degron motif	0.7031
p.V338I	DO42673	UCEC	ICGC	IAPIFGKKARVVI	DEG_ODPH_VHL_1	318:330	Mutation rewiring degron network	0.1111
p.P339S	ACH-000962	Ovarian Cancer	CCLE	IAPIFGKKARVVI	DEG_ODPH_VHL_1	318:330	Mutation rewiring degron network	0.0833
p.P339S	ACH-001145	Ovarian Cancer	CCLE	IAPIFGKKARVVI	DEG_ODPH_VHL_1	318:330	Mutation rewiring degron network	0.0833
p.A326V	ACH-002785	Unknown	CCLE	IAPIFGKKARVVI	DEG_ODPH_VHL_1	318:330	Mutation altering degron motif	0.5825

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons