DegronMD - Q9H819(DNAJC18)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A18T	TCGA-A5-A0G2	UCEC	TCGA	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.1389
p.A18T	DO41235	UCEC	ICGC	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.1389
p.D27G	TCGA-CK-5913	COAD	TCGA	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation altering degron motif	0.6087
p.D27G	DO8826	COAD	ICGC	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation altering degron motif	0.6087
p.R20K	TCGA-CN-4734	HNSC	TCGA	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.1944
p.R20K	DO15446	HNSC	ICGC	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.1944
p.E31A	DO228261	LICA	ICGC	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation altering degron motif	0.659
p.A18E	DO229036	LICA	ICGC	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.1389
p.E31D	DO229242	THCA	ICGC	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation altering degron motif	0.5647
p.H33N	SIDM01007	T-Lymphoblastic Leukemia	GDSC	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.3056
p.H33N	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.3056
p.M42I	SIDM00529	Breast Carcinoma	GDSC	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.0556
p.M42I	MDA-MB-157	breast	COSMIC	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.0556
p.M42T	SIDM00154	Mesothelioma	GDSC	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.0556
p.M42T	ACH-002130	Lung Cancer	CCLE	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.0556
p.M42T	H2795	pleura	COSMIC	PEDTPPES	DEG_SCF_FBW7_1	25:32	Mutation rewiring degron network	0.0556

Kaplan plot for DNAJC18 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

DNAJC18

UniProt ID: Q9H819

Entrez ID: 202052

Protein name: DnaJ homolog subfamily C member 18

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for DNAJC18 in