DegronMD - Q9H9L3(ISG20L2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P103L	TCGA-FW-A3R5	SKCM	TCGA	LTPAPS	DEG_SCF_FBW7_1	101:106	Mutation altering degron motif	0.7582
p.P103L	DO37406	SKCM	ICGC	LTPAPS	DEG_SCF_FBW7_1	101:106	Mutation altering degron motif	0.7582
p.P91H	DO229032	LICA	ICGC	LTPAPS	DEG_SCF_FBW7_1	101:106	Mutation rewiring degron network	0.0556
p.W100L	DO23204	LINC	ICGC	LTPAPS	DEG_SCF_FBW7_1	101:106	Mutation rewiring degron network	0.3056
p.T102I	DO232224	PBCA	ICGC	LTPAPS	DEG_SCF_FBW7_1	101:106	Mutation altering degron motif	0.7078

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons