DegronMD - Q9HAH7(FBRS)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D19N	DO219729	CESC	ICGC	NPYTAFP	CBL_PTK	16:22	Mutation altering degron motif	0.6932
p.G7E	DO48328	ESCA	ICGC	NPYTAFP	CBL_PTK	16:22	Mutation rewiring degron network	0.0833
p.G7E	DO52079	HNSC	ICGC	NPYTAFP	CBL_PTK	16:22	Mutation rewiring degron network	0.0833
p.M16I	DO231207	LUSC	ICGC	NPYTAFP	CBL_PTK	16:22	Mutation altering degron motif	0.7618
p.R26W	DO27067	LUSC	ICGC	NPYTAFP	CBL_PTK	16:22	Mutation rewiring degron network	0.2222
p.P6Q	DO47451	SKCM	ICGC	NPYTAFP	CBL_PTK	16:22	Mutation rewiring degron network	0.0556
p.A24T	DO42033	UCEC	ICGC	NPYTAFP	CBL_PTK	16:22	Mutation rewiring degron network	0.2778
p.R14Q	DO42504	UCEC	ICGC	NPYTAFP	CBL_PTK	16:22	Mutation rewiring degron network	0.2778
p.L29I	DO42673	UCEC	ICGC	NPYTAFP	CBL_PTK	16:22	Mutation rewiring degron network	0.1389
p.C24Y	SIDM02026	Colorectal Carcinoma	GDSC	NPYTAFP	CBL_PTK	16:22	Mutation rewiring degron network	0.2778
p.P23H	ACH-000864	Endometrial/Uterine Cancer	CCLE	NPYTAFP	CBL_PTK	16:22	Mutation rewiring degron network	0.3056
p.P23H	COLO-684	endometrium	COSMIC	NPYTAFP	CBL_PTK	16:22	Mutation rewiring degron network	0.3056
p.R19C	ACH-000965	Endometrial/Uterine Cancer	CCLE	NPYTAFP	CBL_PTK	16:22	Mutation altering degron motif	0.8301
p.P6S	ESO26	oesophagus	COSMIC	NPYTAFP	CBL_PTK	16:22	Mutation rewiring degron network	0.0556
p.P30L	EoL-1-cell	haematopoietic and lymphoid tissue	COSMIC	NPYTAFP	CBL_PTK	16:22	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons