DegronMD - Q9HBM0(VEZT)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A702T	TCGA-A5-A0G1	UCEC	TCGA	PPTPRDS	DEG_SCF_FBW7_1	711:717	Mutation rewiring degron network	0.0833
p.A702T	DO42472	UCEC	ICGC	PPTPRDS	DEG_SCF_FBW7_1	711:717	Mutation rewiring degron network	0.0833
p.L726M	TCGA-B5-A3FA	UCEC	TCGA	PPTPRDS	DEG_SCF_FBW7_1	711:717	Mutation rewiring degron network	0.0833
p.L726M	DO52402	UCEC	ICGC	PPTPRDS	DEG_SCF_FBW7_1	711:717	Mutation rewiring degron network	0.0833
p.P711S	TCGA-BP-4995	KIRC	TCGA	PPTPRDS	DEG_SCF_FBW7_1	711:717	Mutation altering degron motif	0.6752
p.P711S	DO16370	KIRC	ICGC	PPTPRDS	DEG_SCF_FBW7_1	711:717	Mutation altering degron motif	0.6752
p.T708A	TCGA-BR-4368	STAD	TCGA	PPTPRDS	DEG_SCF_FBW7_1	711:717	Mutation rewiring degron network	0.25
p.T708A	DO38715	STAD	ICGC	PPTPRDS	DEG_SCF_FBW7_1	711:717	Mutation rewiring degron network	0.25
p.P720S	TCGA-FW-A3R5	SKCM	TCGA	PPTPRDS	DEG_SCF_FBW7_1	711:717	Mutation rewiring degron network	0.25
p.P720S	DO37406	SKCM	ICGC	PPTPRDS	DEG_SCF_FBW7_1	711:717	Mutation rewiring degron network	0.25
p.I722N	SIDM01111	Ewing's Sarcoma	GDSC	PPTPRDS	DEG_SCF_FBW7_1	711:717	Mutation rewiring degron network	0.1944
p.I722N	ACH-000087	Bone Cancer	CCLE	PPTPRDS	DEG_SCF_FBW7_1	711:717	Mutation rewiring degron network	0.1944
p.I722N	SK-ES-1	bone	COSMIC	PPTPRDS	DEG_SCF_FBW7_1	711:717	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons