DegronMD - Q9HBR0(SLC38A10)

SLC38A10

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R1054W	TCGA-97-7554	LUAD	TCGA	LGPHAE	LIG_APCC_ABBA_1	1056:1061	Mutation rewiring degron network	0.2778
p.R1054W	DO23592	LUAD	ICGC	LGPHAE	LIG_APCC_ABBA_1	1056:1061	Mutation rewiring degron network	0.2778
p.R1050W	TCGA-AA-A01P	COAD	TCGA	LGPHAE	LIG_APCC_ABBA_1	1056:1061	Mutation rewiring degron network	0.1667
p.R1050W	DO8642	COAD	ICGC	LGPHAE	LIG_APCC_ABBA_1	1056:1061	Mutation rewiring degron network	0.1667
p.R1050L	TCGA-D3-A3C7	SKCM	TCGA	LGPHAE	LIG_APCC_ABBA_1	1056:1061	Mutation rewiring degron network	0.1667
p.R1050L	DO47569	SKCM	ICGC	LGPHAE	LIG_APCC_ABBA_1	1056:1061	Mutation rewiring degron network	0.1667
p.H1059Q	DO232846	NACA	ICGC	LGPHAE	LIG_APCC_ABBA_1	1056:1061	Mutation altering degron motif	0.7582
p.G1062R	DO233293	NACA	ICGC	LGPHAE	LIG_APCC_ABBA_1	1056:1061	Mutation rewiring degron network	0.3056
p.Q1063L	DO233296	NACA	ICGC	LGPHAE	LIG_APCC_ABBA_1	1056:1061	Mutation rewiring degron network	0.2778
p.R1054Q	SIDM00059	Ovarian Carcinoma	GDSC	LGPHAE	LIG_APCC_ABBA_1	1056:1061	Mutation rewiring degron network	0.2778
p.P1066S	SIDM01059	Melanoma	GDSC	LGPHAE	LIG_APCC_ABBA_1	1056:1061	Mutation rewiring degron network	0.1944
p.P1066S	ACH-000915	Skin Cancer	CCLE	LGPHAE	LIG_APCC_ABBA_1	1056:1061	Mutation rewiring degron network	0.1944
p.G1069R	ACH-001750	Sarcoma	CCLE	LGPHAE	LIG_APCC_ABBA_1	1056:1061	Mutation rewiring degron network	0.1111
p.R1053W	ACH-002511	Skin Cancer	CCLE	LGPHAE	LIG_APCC_ABBA_1	1056:1061	Mutation rewiring degron network	0.25

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc