DegronMD - Q9HCE5(METTL14)

METTL14

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D125E	TCGA-CU-A3YL	BLCA	TCGA	LNPHND	LIG_APCC_ABBA_1	113:118	Mutation rewiring degron network	0.1389
p.D125E	DO834	BLCA	ICGC	LNPHND	LIG_APCC_ABBA_1	113:118	Mutation rewiring degron network	0.1389
p.Y119C	DO49478	PACA	ICGC	LNPHND	LIG_APCC_ABBA_1	113:118	Mutation rewiring degron network	0.3056
p.P115L	SIDM00221	Melanoma	GDSC	LNPHND	LIG_APCC_ABBA_1	113:118	Mutation altering degron motif	0.6471
p.P115L	ACH-002388	Skin Cancer	CCLE	LNPHND	LIG_APCC_ABBA_1	113:118	Mutation altering degron motif	0.6471
p.T126S	SIDM00892	Breast Carcinoma	GDSC	LNPHND	LIG_APCC_ABBA_1	113:118	Mutation rewiring degron network	0.1111
p.T126S	ACH-000818	Breast Cancer	CCLE	LNPHND	LIG_APCC_ABBA_1	113:118	Mutation rewiring degron network	0.1111
p.T126S	BT-483	breast	COSMIC	LNPHND	LIG_APCC_ABBA_1	113:118	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc