DegronMD - Q9HCH3(CPNE5)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T591M	TCGA-CD-8536	STAD	TCGA	PARTPPAS	DEG_SCF_FBW7_1	580:587	Mutation rewiring degron network	0.2222
p.T591M	DO47827	STAD	ICGC	PARTPPAS	DEG_SCF_FBW7_1	580:587	Mutation rewiring degron network	0.2222
p.P584R	TCGA-E2-A14W	BRCA	TCGA	PARTPPAS	DEG_SCF_FBW7_1	580:587	Mutation altering degron motif	0.7512
p.P584R	DO4281	BRCA	ICGC	PARTPPAS	DEG_SCF_FBW7_1	580:587	Mutation altering degron motif	0.7512
p.A581V	TCGA-IB-A7M4	PAAD	TCGA	PARTPPAS	DEG_SCF_FBW7_1	580:587	Mutation altering degron motif	0.5825
p.A581V	DO50261	PAAD	ICGC	PARTPPAS	DEG_SCF_FBW7_1	580:587	Mutation altering degron motif	0.5825
p.R582H	DO230347	COCA	ICGC	PARTPPAS	DEG_SCF_FBW7_1	580:587	Mutation altering degron motif	0.7133
p.R582H	SIDM00216	Colorectal Carcinoma	GDSC	PARTPPAS	DEG_SCF_FBW7_1	580:587	Mutation altering degron motif	0.7133
p.R582H	SIDM00410	Other Blood Cancers	GDSC	PARTPPAS	DEG_SCF_FBW7_1	580:587	Mutation altering degron motif	0.7133
p.R582H	SIDM00469	Pancreatic Carcinoma	GDSC	PARTPPAS	DEG_SCF_FBW7_1	580:587	Mutation altering degron motif	0.7133
p.R582H	SIDM00986	Head and Neck Carcinoma	GDSC	PARTPPAS	DEG_SCF_FBW7_1	580:587	Mutation altering degron motif	0.7133
p.S575L	DO233867	GACA	ICGC	PARTPPAS	DEG_SCF_FBW7_1	580:587	Mutation rewiring degron network	0.1944
p.S579Y	DO228948	LICA	ICGC	PARTPPAS	DEG_SCF_FBW7_1	580:587	Mutation rewiring degron network	0.3056
p.P572Q	DO228974	LICA	ICGC	PARTPPAS	DEG_SCF_FBW7_1	580:587	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons