DegronMD - Q9HCK0(ZBTB26)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M361I	TCGA-09-2044	OV	TCGA	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation rewiring degron network	0.1111
p.M361I	DO28923	OV	ICGC	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation rewiring degron network	0.1111
p.V362F	TCGA-D1-A103	UCEC	TCGA	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation rewiring degron network	0.1389
p.V362F	DO42312	UCEC	ICGC	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation rewiring degron network	0.1389
p.E387D	DO224847	BRCA	ICGC	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation rewiring degron network	0.0556
p.E387D	DO227473	BRCA	ICGC	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation rewiring degron network	0.0556
p.N384I	DO227549	COCA	ICGC	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation rewiring degron network	0.1389
p.H372N	DO229027	LICA	ICGC	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation altering degron motif	0.6312
p.V368A	DO23108	LINC	ICGC	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation rewiring degron network	0.3056
p.V368A	DO45041	LINC	ICGC	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation rewiring degron network	0.3056
p.H377N	SIDM00144	Non-Small Cell Lung Carcinoma	GDSC	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation altering degron motif	0.6312
p.H377N	ACH-000463	Lung Cancer	CCLE	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation altering degron motif	0.6312
p.H377N	NCI-H460	lung	COSMIC	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation altering degron motif	0.6312
p.R370M	SIDM00683	Prostate Carcinoma	GDSC	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation altering degron motif	0.8632
p.R370M	LNCaP-Clone-FGC	prostate	COSMIC	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation altering degron motif	0.8632
p.E387K	SIDM00220	Ovarian Carcinoma	GDSC	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation rewiring degron network	0.0556
p.E387K	ACH-000962	Ovarian Cancer	CCLE	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation rewiring degron network	0.0556
p.E387K	ACH-001145	Ovarian Cancer	CCLE	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation rewiring degron network	0.0556
p.E387K	OC-314	ovary	COSMIC	LRKHLKQLH	DEG_APCC_DBOX_1	369:377	Mutation rewiring degron network	0.0556

Kaplan plot for ZBTB26 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ZBTB26

UniProt ID: Q9HCK0

Entrez ID: 57684

Protein name: Zinc finger and BTB domain-containing protein 26 (Zinc finger protein 481) (Zinc finger protein Bioref)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ZBTB26 in