DegronMD - Q9HD15(SRA1)

SRA1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L183I	TCGA-18-3412	LUSC	TCGA	KRSLFSE	LIG_APCC_ABBAyCdc20_2	193:199	Mutation rewiring degron network	0.0556
p.L183I	TCGA-23-1121	OV	TCGA	KRSLFSE	LIG_APCC_ABBAyCdc20_2	193:199	Mutation rewiring degron network	0.0556
p.L183I	DO26552	LUSC	ICGC	KRSLFSE	LIG_APCC_ABBAyCdc20_2	193:199	Mutation rewiring degron network	0.0556
p.L183I	DO28731	OV	ICGC	KRSLFSE	LIG_APCC_ABBAyCdc20_2	193:199	Mutation rewiring degron network	0.0556
p.E190Q	TCGA-92-8065	LUSC	TCGA	KRSLFSE	LIG_APCC_ABBAyCdc20_2	193:199	Mutation rewiring degron network	0.25
p.E190Q	DO27074	LUSC	ICGC	KRSLFSE	LIG_APCC_ABBAyCdc20_2	193:199	Mutation rewiring degron network	0.25
p.R206M	TCGA-A5-A0G2	UCEC	TCGA	KRSLFSE	LIG_APCC_ABBAyCdc20_2	193:199	Mutation substituting flanking lysine	0.25
p.R206M	DO41235	UCEC	ICGC	KRSLFSE	LIG_APCC_ABBAyCdc20_2	193:199	Mutation substituting flanking lysine	0.25
p.E190K	TCGA-AC-A5XS	BRCA	TCGA	KRSLFSE	LIG_APCC_ABBAyCdc20_2	193:199	Mutation rewiring degron network	0.25
p.E190K	DO50023	BRCA	ICGC	KRSLFSE	LIG_APCC_ABBAyCdc20_2	193:199	Mutation rewiring degron network	0.25
p.R200T	SIDM00684	Glioblastoma	GDSC	KRSLFSE	LIG_APCC_ABBAyCdc20_2	193:199	Mutation rewiring degron network	0.3056
p.R200T	LN-229	central nervous system	COSMIC	KRSLFSE	LIG_APCC_ABBAyCdc20_2	193:199	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc