DegronMD - Q9NP08(HMX1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T149A	DO233259	GACA	ICGC	SPETGE	DEG_Kelch_Keap1_1	137:142	Mutation rewiring degron network	0.1389
p.S133R	DO26553	LUSC	ICGC	SPETGE	DEG_Kelch_Keap1_1	137:142	Mutation rewiring degron network	0.2222
p.D152N	DO222546	MELA	ICGC	SPETGE	DEG_Kelch_Keap1_1	137:142	Mutation rewiring degron network	0.0556
p.A151T	DO222775	MELA	ICGC	SPETGE	DEG_Kelch_Keap1_1	137:142	Mutation rewiring degron network	0.0833
p.V148L	DO229275	THCA	ICGC	SPETGE	DEG_Kelch_Keap1_1	137:142	Mutation rewiring degron network	0.1667
p.P152Q	ACH-000669	Lung Cancer	CCLE	SPETGE	DEG_Kelch_Keap1_1	137:142	Mutation rewiring degron network	0.0556
p.G141C	ACH-000852	Lung Cancer	CCLE	SPETGE	DEG_Kelch_Keap1_1	137:142	Mutation altering degron motif	0.76
p.P152L	ACH-000940	Endometrial/Uterine Cancer	CCLE	SPETGE	DEG_Kelch_Keap1_1	137:142	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons