DegronMD - Q9NP85(NPHS2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A5V	TCGA-CM-5861	COAD	TCGA	ARSSS	DEG_SPOP_SBC_1	5:9	Mutation altering degron motif	0.5825
p.A5V	DO7918	COAD	ICGC	ARSSS	DEG_SPOP_SBC_1	5:9	Mutation altering degron motif	0.5825
p.R15Q	DO477	BLCA	ICGC	ARSSS	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.1667
p.R6Q	DO219873	SKCA	ICGC	ARSSS	DEG_SPOP_SBC_1	5:9	Mutation altering degron motif	0.6218
p.R10T	SIDM01175	Other Sarcomas	GDSC	ARSSS	DEG_SPOP_SBC_1	5:9	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons