DegronMD - Q9NPC6(MYOZ2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A104S	TCGA-AA-3966	COAD	TCGA	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation rewiring degron network	0.3056
p.A104S	DO10068	COAD	ICGC	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation rewiring degron network	0.3056
p.P109S	TCGA-D3-A3MR	SKCM	TCGA	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation altering degron motif	0.5641
p.P109S	DO47256	SKCM	ICGC	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation altering degron motif	0.5641
p.S101T	TCGA-DD-AAW2	LIHC	TCGA	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation rewiring degron network	0.2222
p.S101T	DO52288	LIHC	ICGC	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation rewiring degron network	0.2222
p.S101L	TCGA-EE-A29D	SKCM	TCGA	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation rewiring degron network	0.2222
p.S101L	TCGA-FW-A3R5	SKCM	TCGA	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation rewiring degron network	0.2222
p.S101L	DO37406	SKCM	ICGC	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation rewiring degron network	0.2222
p.S101L	DO38123	SKCM	ICGC	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation rewiring degron network	0.2222
p.S101L	SIDM00392	Melanoma	GDSC	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation rewiring degron network	0.2222
p.S101L	ACH-000810	Skin Cancer	CCLE	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation rewiring degron network	0.2222
p.S101L	SK-MEL-30	skin	COSMIC	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation rewiring degron network	0.2222
p.S95N	DO227970	COCA	ICGC	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation rewiring degron network	0.0556
p.N119H	SIDM01588	Endometrial Carcinoma	GDSC	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation rewiring degron network	0.1111
p.N119H	ACH-000993	Endometrial/Uterine Cancer	CCLE	PLTPPNT	DEG_SCF_FBW7_1	105:111	Mutation rewiring degron network	0.1111

Kaplan plot for MYOZ2 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MYOZ2

UniProt ID: Q9NPC6

Entrez ID: 51778

Protein name: Myozenin-2 (Calsarcin-1) (FATZ-related protein 2)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for MYOZ2 in