DegronMD - Q9NPC7(MYNN)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S233L	TCGA-BP-4964	KIRC	TCGA	LPTPVVE	DEG_SCF_FBW7_2	218:224	Mutation rewiring degron network	0.0833
p.S233L	DO16263	KIRC	ICGC	LPTPVVE	DEG_SCF_FBW7_2	218:224	Mutation rewiring degron network	0.0833
p.D214H	TCGA-PG-A914	UCEC	TCGA	LPTPVVE	DEG_SCF_FBW7_2	218:224	Mutation rewiring degron network	0.2222
p.D214H	DO52421	UCEC	ICGC	LPTPVVE	DEG_SCF_FBW7_2	218:224	Mutation rewiring degron network	0.2222
p.V222L	DO229038	LICA	ICGC	LPTPVVE	DEG_SCF_FBW7_2	218:224	Mutation altering degron motif	0.5654
p.N216D	DO48697	LIRI	ICGC	LPTPVVE	DEG_SCF_FBW7_2	218:224	Mutation rewiring degron network	0.2778
p.A215E	SIDM00324	Neuroblastoma	GDSC	LPTPVVE	DEG_SCF_FBW7_2	218:224	Mutation rewiring degron network	0.25
p.A215E	ACH-001674	Neuroblastoma	CCLE	LPTPVVE	DEG_SCF_FBW7_2	218:224	Mutation rewiring degron network	0.25
p.A215E	TGW	autonomic ganglia	COSMIC	LPTPVVE	DEG_SCF_FBW7_2	218:224	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons