DegronMD - Q9NPG4(PCDH12)

PCDH12

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S175Y	TCGA-AG-A002	READ	TCGA	NTLHTYTLSP	CBL_PTK	167:176	Mutation altering degron motif	0.6009
p.A181V	TCGA-WS-AB45	COAD	TCGA	NTLHTYTLSP	CBL_PTK	167:176	Mutation rewiring degron network	0.1944
p.A181V	DO51734	COAD	ICGC	NTLHTYTLSP	CBL_PTK	167:176	Mutation rewiring degron network	0.1944
p.D163Y	DO50331	ESAD	ICGC	NTLHTYTLSP	CBL_PTK	167:176	Mutation rewiring degron network	0.2222
p.D163E	DO228952	LICA	ICGC	NTLHTYTLSP	CBL_PTK	167:176	Mutation rewiring degron network	0.2222
p.N167K	DO229034	LICA	ICGC	NTLHTYTLSP	CBL_PTK	167:176	Mutation altering degron motif	0.6918
p.T168N	DO229008	LICA	ICGC	NTLHTYTLSP	CBL_PTK	167:176	Mutation altering degron motif	0.5944
p.T168I	SIDM00579	Neuroblastoma	GDSC	NTLHTYTLSP	CBL_PTK	167:176	Mutation altering degron motif	0.5966
p.T168I	ACH-002277	Neuroblastoma	CCLE	NTLHTYTLSP	CBL_PTK	167:176	Mutation altering degron motif	0.5966
p.T168I	NB(TU)1-10	autonomic ganglia	COSMIC	NTLHTYTLSP	CBL_PTK	167:176	Mutation altering degron motif	0.5966

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*NOTE: the Kaplan plots were collected from OncoLnc