DegronMD - Q9NQH7(XPNPEP3)

XPNPEP3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R59T	TCGA-66-2773	LUSC	TCGA	VTPGLS	DEG_SCF_FBW7_1	63:68	Mutation rewiring degron network	0.2222
p.R75H	TCGA-AA-3510	COAD	TCGA	VTPGLS	DEG_SCF_FBW7_1	63:68	Mutation rewiring degron network	0.1389
p.R75H	SIDM01551	Gastric Carcinoma	GDSC	VTPGLS	DEG_SCF_FBW7_1	63:68	Mutation rewiring degron network	0.1389
p.R75H	ACH-000485	Gastric Cancer	CCLE	VTPGLS	DEG_SCF_FBW7_1	63:68	Mutation rewiring degron network	0.1389
p.P55S	TCGA-CV-7242	HNSC	TCGA	VTPGLS	DEG_SCF_FBW7_1	63:68	Mutation rewiring degron network	0.1111
p.Q72H	DO1080	BRCA	ICGC	VTPGLS	DEG_SCF_FBW7_1	63:68	Mutation rewiring degron network	0.2222
p.L59M	DO10880	GBM	ICGC	VTPGLS	DEG_SCF_FBW7_1	63:68	Mutation rewiring degron network	0.2222
p.G66W	DO228952	LICA	ICGC	VTPGLS	DEG_SCF_FBW7_1	63:68	Mutation altering degron motif	0.6714
p.S68R	DO45259	LIRI	ICGC	VTPGLS	DEG_SCF_FBW7_1	63:68	Mutation altering degron motif	0.7427
p.V75A	DO51783	STAD	ICGC	VTPGLS	DEG_SCF_FBW7_1	63:68	Mutation rewiring degron network	0.1389
p.L67P	SIDM01314	Colorectal Carcinoma	GDSC	VTPGLS	DEG_SCF_FBW7_1	63:68	Mutation altering degron motif	0.6471
p.R75G	SIDM00523	Small Cell Lung Carcinoma	GDSC	VTPGLS	DEG_SCF_FBW7_1	63:68	Mutation rewiring degron network	0.1389
p.R75G	ACH-000698	Lung Cancer	CCLE	VTPGLS	DEG_SCF_FBW7_1	63:68	Mutation rewiring degron network	0.1389
p.R75G	DMS-53	lung	COSMIC	VTPGLS	DEG_SCF_FBW7_1	63:68	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc