FUNCTION: Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3 (By similarity). Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR (By similarity). Forms with BHLHE22 a transcriptional ...
FUNCTION: Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3 (By similarity). Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR (By similarity). Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation (By similarity). In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival (By similarity). {ECO:0000250|UniProtKB:Q8BZ97}.
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GO - Biological processes (BP):
methylation [GO:0032259]; oligodendrocyte development [GO:0014003]; regulation of transcription, DNA-templated [GO:0006355]...
methylation [GO:0032259]; oligodendrocyte development [GO:0014003]; regulation of transcription, DNA-templated [GO:0006355]
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GO - Molecular function (MF):
DNA binding [GO:0003677]; metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]...
DNA binding [GO:0003677]; metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]
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GO - Cellular component (CC):
nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]...
nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]
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