DegronMD - Q9NQX5(NPDC1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G149R	TCGA-A5-A2K7	UCEC	TCGA	PGTPTPT	DEG_SCF_FBW7_1	148:154	Mutation altering degron motif	0.6457
p.R161H	DO10880	GBM	ICGC	PGTPTPT	DEG_SCF_FBW7_1	148:154	Mutation rewiring degron network	0.1389
p.P158T	DO229041	LICA	ICGC	PGTPTPT	DEG_SCF_FBW7_1	148:154	Mutation rewiring degron network	0.2222
p.P147T	DO229063	LICA	ICGC	PGTPTPT	DEG_SCF_FBW7_1	148:154	Mutation rewiring degron network	0.3056
p.R161C	DO51407	PRAD	ICGC	PGTPTPT	DEG_SCF_FBW7_1	148:154	Mutation rewiring degron network	0.1389
p.G139E	SIDM00403	T-Lymphoblastic Leukemia	GDSC	PGTPTPT	DEG_SCF_FBW7_1	148:154	Mutation rewiring degron network	0.0833
p.G139E	ACH-000636	Leukemia	CCLE	PGTPTPT	DEG_SCF_FBW7_1	148:154	Mutation rewiring degron network	0.0833
p.G139E	RPMI-8402	haematopoietic and lymphoid tissue	COSMIC	PGTPTPT	DEG_SCF_FBW7_1	148:154	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons