DegronMD - Q9NQZ2(UTP3)

UTP3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V123M	TCGA-66-2794	LUSC	TCGA	RKKLYYD	LIG_APCC_ABBAyCdc20_2	132:138	Mutation rewiring degron network	0.0833
p.V123M	DO26683	LUSC	ICGC	RKKLYYD	LIG_APCC_ABBAyCdc20_2	132:138	Mutation rewiring degron network	0.0833
p.R148W	TCGA-A5-A0G2	UCEC	TCGA	RKKLYYD	LIG_APCC_ABBAyCdc20_2	132:138	Mutation rewiring degron network	0.0556
p.R148W	DO41235	UCEC	ICGC	RKKLYYD	LIG_APCC_ABBAyCdc20_2	132:138	Mutation rewiring degron network	0.0556
p.R146P	TCGA-E7-A7DV	BLCA	TCGA	RKKLYYD	LIG_APCC_ABBAyCdc20_2	132:138	Mutation rewiring degron network	0.1111
p.R146P	DO48583	BLCA	ICGC	RKKLYYD	LIG_APCC_ABBAyCdc20_2	132:138	Mutation rewiring degron network	0.1111
p.R146Q	TCGA-VR-A8EW	ESCA	TCGA	RKKLYYD	LIG_APCC_ABBAyCdc20_2	132:138	Mutation rewiring degron network	0.1111
p.T139M	DO228313	LICA	ICGC	RKKLYYD	LIG_APCC_ABBAyCdc20_2	132:138	Mutation blocking phosphorylation signal	0.75
p.Y141C	DO229234	THCA	ICGC	RKKLYYD	LIG_APCC_ABBAyCdc20_2	132:138	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc