DegronMD - Q9NR22(PRMT8)

PRMT8

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R394C	TCGA-4X-A9FC	THYM	TCGA	KMR	DEG_APCC_TPR_1	392:394	Mutation altering degron motif	0.8301
p.R394C	TCGA-AG-3891	READ	TCGA	KMR	DEG_APCC_TPR_1	392:394	Mutation altering degron motif	0.8301
p.R394C	TCGA-BH-A0DI	BRCA	TCGA	KMR	DEG_APCC_TPR_1	392:394	Mutation altering degron motif	0.8301
p.L382M	TCGA-AP-A059	UCEC	TCGA	KMR	DEG_APCC_TPR_1	392:394	Mutation rewiring degron network	0.0556
p.E384K	TCGA-ER-A19F	SKCM	TCGA	KMR	DEG_APCC_TPR_1	392:394	Mutation rewiring degron network	0.1111
p.D390G	TCGA-F7-A624	HNSC	TCGA	KMR	DEG_APCC_TPR_1	392:394	Mutation rewiring degron network	0.2778
p.S388F	TCGA-T3-A92M	HNSC	TCGA	KMR	DEG_APCC_TPR_1	392:394	Mutation rewiring degron network	0.2222
p.R385C	DO2281	BRCA	ICGC	KMR	DEG_APCC_TPR_1	392:394	Mutation rewiring degron network	0.1389
p.R385C	DO51527	PACA	ICGC	KMR	DEG_APCC_TPR_1	392:394	Mutation rewiring degron network	0.1389
p.R385C	DO36388	READ	ICGC	KMR	DEG_APCC_TPR_1	392:394	Mutation rewiring degron network	0.1389
p.R394H	SIDM00099	Mesothelioma	GDSC	KMR	DEG_APCC_TPR_1	392:394	Mutation altering degron motif	0.8244
p.R394H	ACH-002128	Lung Cancer	CCLE	KMR	DEG_APCC_TPR_1	392:394	Mutation altering degron motif	0.8244
p.R394H	H2722	pleura	COSMIC	KMR	DEG_APCC_TPR_1	392:394	Mutation altering degron motif	0.8244
p.R385H	H2722	pleura	COSMIC	KMR	DEG_APCC_TPR_1	392:394	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc