DegronMD - Q9NRH1(YAE1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q31R	SIDM01314	Colorectal Carcinoma	GDSC	KGDVFDE	LIG_APCC_ABBAyCdc20_2	16:22	Mutation rewiring degron network	0.0833
p.A30V	SIDM00945	Colorectal Carcinoma	GDSC	KGDVFDE	LIG_APCC_ABBAyCdc20_2	16:22	Mutation rewiring degron network	0.1111
p.A30V	CL-34	large intestine	COSMIC	KGDVFDE	LIG_APCC_ABBAyCdc20_2	16:22	Mutation rewiring degron network	0.1111
p.P13S	SIDM00807	Bladder Carcinoma	GDSC	KGDVFDE	LIG_APCC_ABBAyCdc20_2	16:22	Mutation rewiring degron network	0.25
p.D21E	SIDM00213	Thyroid Gland Carcinoma	GDSC	KGDVFDE	LIG_APCC_ABBAyCdc20_2	16:22	Mutation altering degron motif	0.5647
p.D21E	SIDM00228	Thyroid Gland Carcinoma	GDSC	KGDVFDE	LIG_APCC_ABBAyCdc20_2	16:22	Mutation altering degron motif	0.5647
p.D21E	FTC-133	thyroid	COSMIC	KGDVFDE	LIG_APCC_ABBAyCdc20_2	16:22	Mutation altering degron motif	0.5647

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons