DegronMD - Q9NS62(THSD1)

THSD1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A715V	TCGA-B5-A3FC	UCEC	TCGA	TRGPLNPLP	DEG_APCC_DBOX_1	718:726	Mutation rewiring degron network	0.25
p.L709M	TCGA-D1-A103	UCEC	TCGA	TRGPLNPLP	DEG_APCC_DBOX_1	718:726	Mutation rewiring degron network	0.0833
p.P726S	TCGA-EE-A20H	SKCM	TCGA	TRGPLNPLP	DEG_APCC_DBOX_1	718:726	Mutation altering degron motif	0.5641
p.P726S	TCGA-EE-A3J4	SKCM	TCGA	TRGPLNPLP	DEG_APCC_DBOX_1	718:726	Mutation altering degron motif	0.5641
p.P724H	TCGA-FP-A4BE	STAD	TCGA	TRGPLNPLP	DEG_APCC_DBOX_1	718:726	Mutation altering degron motif	0.6583
p.Q733K	SIDM01144	Gastric Carcinoma	GDSC	TRGPLNPLP	DEG_APCC_DBOX_1	718:726	Mutation rewiring degron network	0.1389
p.Q733K	ACH-000303	Gastric Cancer	CCLE	TRGPLNPLP	DEG_APCC_DBOX_1	718:726	Mutation rewiring degron network	0.1389
p.Q733K	NCI-SNU-5	stomach	COSMIC	TRGPLNPLP	DEG_APCC_DBOX_1	718:726	Mutation rewiring degron network	0.1389
p.S716G	SIDM00566	Oral Cavity Carcinoma	GDSC	TRGPLNPLP	DEG_APCC_DBOX_1	718:726	Mutation rewiring degron network	0.2778
p.S716G	ACH-001625	Head and Neck Cancer	CCLE	TRGPLNPLP	DEG_APCC_DBOX_1	718:726	Mutation rewiring degron network	0.2778
p.S716G	OSC-19	upper aerodigestive tract	COSMIC	TRGPLNPLP	DEG_APCC_DBOX_1	718:726	Mutation rewiring degron network	0.2778
p.S736Y	CW-2	large intestine	COSMIC	TRGPLNPLP	DEG_APCC_DBOX_1	718:726	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc