DegronMD - Q9NTN9(SEMA4G)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R338H	TCGA-ER-A3ES	SKCM	TCGA	CRYDLAEIQ	DEG_APCC_DBOX_1	337:345	Mutation altering degron motif	0.8244
p.R338H	DO227657	COCA	ICGC	CRYDLAEIQ	DEG_APCC_DBOX_1	337:345	Mutation altering degron motif	0.8244
p.R338H	DO47546	SKCM	ICGC	CRYDLAEIQ	DEG_APCC_DBOX_1	337:345	Mutation altering degron motif	0.8244
p.G350E	DO222595	MELA	ICGC	CRYDLAEIQ	DEG_APCC_DBOX_1	337:345	Mutation rewiring degron network	0.1944
p.L331V	SIDM01735	Biliary Tract Carcinoma	GDSC	CRYDLAEIQ	DEG_APCC_DBOX_1	337:345	Mutation rewiring degron network	0.1667
p.L331V	SIDM01473	Plasma Cell Myeloma	GDSC	CRYDLAEIQ	DEG_APCC_DBOX_1	337:345	Mutation rewiring degron network	0.1667
p.Q345H	ACH-001719	Ovarian Cancer	CCLE	CRYDLAEIQ	DEG_APCC_DBOX_1	337:345	Mutation altering degron motif	0.647

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons