CATSPERZ
UniProt ID: Q9NTU4
Entrez ID: 25858
Protein name: Cation channel sperm-associated auxiliary subunit zeta (CatSper-zeta) (CatSperzeta) (Testis-expressed protein 40)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for a distribution of the CatSper complex in linear quadrila...
FUNCTION: Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for a distribution of the CatSper complex in linear quadrilateral nanodomains along the flagellum, maximizing fertilization inside the mammalian female reproductive tract. Together with EFCAB9, associates with the CatSper channel pore and is required for the two-row structure of each single CatSper channel. {ECO:0000250|UniProtKB:Q9CQP8}.
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GO - Biological processes (BP):
flagellated sperm motility [GO:0030317]; male meiotic nuclear division [GO:0007140]; spermatogenesis [GO:0007283]; sperm capacitation [GO:0048240]...
flagellated sperm motility [GO:0030317]; male meiotic nuclear division [GO:0007140]; spermatogenesis [GO:0007283]; sperm capacitation [GO:0048240]
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GO - Molecular function (MF):
...
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GO - Cellular component (CC):
CatSper complex [GO:0036128]; cytoplasm [GO:0005737]; sperm principal piece [GO:0097228]...
CatSper complex [GO:0036128]; cytoplasm [GO:0005737]; sperm principal piece [GO:0097228]
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CATSPERZ
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*NOTE: the Kaplan plots were collected from OncoLnc