DegronMD

Uniprot ID: Q9NTU4

Source protein: Cation channel sperm-associated auxiliary subunit zeta

Source gene: CATSPERZ

Class: DEG_APCC_DBOX_1

Location: 143:151

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9481

ASA_SCORE: 71.7333

COIL: 0.5773

CONS_SCORE: 0.9486

DSS_SCORE: 0.2033

HELIX: 0.3952

FCONS_SCORE: 1.1905

RIG_SCORE: 0.7984

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R135Q	A431	skin	COSMIC	SRLPLPLME	DEG_APCC_DBOX_1	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9NTU4	Cation channel sperm-associated auxiliary subunit zeta	DEG_APCC_DBOX_1	143:151	SRLPLPLME	APC,CDC20,FZR1	0.9481	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons