DegronMD - Q9NTU7(CBLN4)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R5C	DO234416	ESAD	ICGC	GRRALSAVP	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.8301
p.R6G	DO229242	THCA	ICGC	GRRALSAVP	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.6457
p.G4A	SIDM00845	Burkitt's Lymphoma	GDSC	GRRALSAVP	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.6429
p.R5H	SIDM01113	Other Sarcomas	GDSC	GRRALSAVP	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.8244
p.R5H	ACH-000939	Sarcoma	CCLE	GRRALSAVP	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.8244
p.A13T	SIDM01662	Plasma Cell Myeloma	GDSC	GRRALSAVP	DEG_APCC_DBOX_1	4:12	Mutation rewiring degron network	0.3056
p.A10V	SIDM01424	B-Lymphoblastic Leukemia	GDSC	GRRALSAVP	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.5825
p.A10V	ACH-001735	Leukemia	CCLE	GRRALSAVP	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.5825
p.A7E	ACH-000616	Gastric Cancer	CCLE	GRRALSAVP	DEG_APCC_DBOX_1	4:12	Mutation altering degron motif	0.659

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons