DegronMD - Q9NU39(FOXD4L1)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G22E	TCGA-A5-A0G2	UCEC	TCGA	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation rewiring degron network	0.1667
p.G22E	DO41235	UCEC	ICGC	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation rewiring degron network	0.1667
p.G22E	SIDM01060	Melanoma	GDSC	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation rewiring degron network	0.1667
p.R15C	TCGA-AP-A1DK	UCEC	TCGA	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation altering degron motif	0.719
p.R15C	DO42033	UCEC	ICGC	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation altering degron motif	0.719
p.R256K	TCGA-B5-A1MR	UCEC	TCGA	PPRY	ITCH	266:269	Mutation rewiring degron network	0.0556
p.R256K	DO41758	UCEC	ICGC	PPRY	ITCH	266:269	Mutation rewiring degron network	0.0556
p.R257H	TCGA-B5-A1MR	UCEC	TCGA	PPRY	ITCH	266:269	Mutation rewiring degron network	0.0833
p.R257H	DO41758	UCEC	ICGC	PPRY	ITCH	266:269	Mutation rewiring degron network	0.0833
p.R18Q	TCGA-BR-8591	STAD	TCGA	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation rewiring degron network	0.2778
p.R18Q	DO47973	STAD	ICGC	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation rewiring degron network	0.2778
p.H263Y	TCGA-CJ-4902	KIRC	TCGA	PPRY	ITCH	266:269	Mutation rewiring degron network	0.25
p.H263Y	DO17693	KIRC	ICGC	PPRY	ITCH	266:269	Mutation rewiring degron network	0.25
p.P264L	TCGA-D1-A1O7	UCEC	TCGA	PPRY	ITCH	266:269	Mutation rewiring degron network	0.2778
p.P264L	DO41139	UCEC	ICGC	PPRY	ITCH	266:269	Mutation rewiring degron network	0.2778
p.R8H	TCGA-FA-A7Q1	DLBC	TCGA	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation rewiring degron network	0.3056
p.R8H	DO219890	DLBC	ICGC	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation rewiring degron network	0.3056
p.R8H	SIDM00789	Colorectal Carcinoma	GDSC	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation rewiring degron network	0.3056
p.R8H	ACH-000997	Colon/Colorectal Cancer	CCLE	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation rewiring degron network	0.3056
p.R8H	HCT-15	large intestine	COSMIC	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation rewiring degron network	0.3056
p.P9L	DO229013	COCA	ICGC	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation altering degron motif	0.6471
p.P9L	DO229003	COCA	ICGC	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation altering degron motif	0.6471
p.P9L	DO51035	LAML	ICGC	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation altering degron motif	0.6471
p.Y259C	DO35242	PACA	ICGC	PPRY	ITCH	266:269	Mutation rewiring degron network	0.1389
p.P13L	SIDM01951	Colorectal Carcinoma	GDSC	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation altering degron motif	0.7582
p.R268C	SIDM00532	Glioma	GDSC	PPRY	ITCH	266:269	Mutation altering degron motif	0.719
p.R268C	ACH-001125	Brain Cancer	CCLE	PPRY	ITCH	266:269	Mutation altering degron motif	0.719
p.R268C	MOG-G-CCM	central nervous system	COSMIC	PPRY	ITCH	266:269	Mutation altering degron motif	0.719
p.R8G	SIDM01018	Hodgkin's Lymphoma	GDSC	PRSTPQRS	DEG_SCF_FBW7_1	9:16	Mutation rewiring degron network	0.3056
p.L262R	NCI-H1048	lung	COSMIC	PPRY	ITCH	266:269	Mutation rewiring degron network	0.2222

Kaplan plot for FOXD4L1 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

FOXD4L1

UniProt ID: Q9NU39

Entrez ID: 200350

Protein name: Forkhead box protein D4-like 1 (FOXD4-like 1)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for FOXD4L1 in