DegronMD - Q9NUB1(ACSS1)

ACSS1

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.W91L	TCGA-ER-A19P	SKCM	TCGA	VWDTPYHT	DEG_SCF_FBW7_1	82:89	Mutation rewiring degron network	0.2778
p.W91L	DO47623	SKCM	ICGC	VWDTPYHT	DEG_SCF_FBW7_1	82:89	Mutation rewiring degron network	0.2778
p.L76P	TCGA-F1-6874	STAD	TCGA	VWDTPYHT	DEG_SCF_FBW7_1	82:89	Mutation rewiring degron network	0.1667
p.L76P	DO38201	STAD	ICGC	VWDTPYHT	DEG_SCF_FBW7_1	82:89	Mutation rewiring degron network	0.1667
p.G98V	SIDM00683	Prostate Carcinoma	GDSC	VWDTPYHT	DEG_SCF_FBW7_1	82:89	Mutation rewiring degron network	0.0833
p.G98V	ACH-000977	lymph node	CCLE	VWDTPYHT	DEG_SCF_FBW7_1	82:89	Mutation rewiring degron network	0.0833
p.G98D	SIDM00901	Endometrial Carcinoma	GDSC	VWDTPYHT	DEG_SCF_FBW7_1	82:89	Mutation rewiring degron network	0.0833
p.G98D	ACH-000940	Endometrial/Uterine Cancer	CCLE	VWDTPYHT	DEG_SCF_FBW7_1	82:89	Mutation rewiring degron network	0.0833
p.G98D	AN3-CA	endometrium	COSMIC	VWDTPYHT	DEG_SCF_FBW7_1	82:89	Mutation rewiring degron network	0.0833
p.V90A	ACH-001081	Colon/Colorectal Cancer	CCLE	VWDTPYHT	DEG_SCF_FBW7_1	82:89	Mutation rewiring degron network	0.3056
p.V90A	HCC2998	large intestine	COSMIC	VWDTPYHT	DEG_SCF_FBW7_1	82:89	Mutation rewiring degron network	0.3056
p.D84Y	ACH-001623	Brain Cancer	CCLE	VWDTPYHT	DEG_SCF_FBW7_1	82:89	Mutation altering degron motif	0.6214

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc