DegronMD - Q9NUQ7(UFSP2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.H238N	TCGA-BT-A20Q	BLCA	TCGA	YRKELHDLF	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.2222
p.H238N	DO695	BLCA	ICGC	YRKELHDLF	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.2222
p.D239N	TCGA-EI-6917	READ	TCGA	YRKELHDLF	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1944
p.D239N	TCGA-FI-A2D5	UCEC	TCGA	YRKELHDLF	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1944
p.D239N	DO36881	READ	ICGC	YRKELHDLF	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1944
p.D239N	DO41331	UCEC	ICGC	YRKELHDLF	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1944
p.H238P	DO50785	LIRI	ICGC	YRKELHDLF	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.2222
p.D239Y	DO50785	LIRI	ICGC	YRKELHDLF	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1944
p.G221C	SIDM00396	Acute Myeloid Leukemia	GDSC	YRKELHDLF	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1944
p.G221C	ACH-000112	Leukemia	CCLE	YRKELHDLF	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1944
p.G221C	SIG-M5	haematopoietic and lymphoid tissue	COSMIC	YRKELHDLF	DEG_APCC_DBOX_1	226:234	Mutation rewiring degron network	0.1944
p.D232Y	ACH-000996	Endometrial/Uterine Cancer	CCLE	YRKELHDLF	DEG_APCC_DBOX_1	226:234	Mutation altering degron motif	0.6214
p.E229D	ACH-001521	Skin Cancer	CCLE	YRKELHDLF	DEG_APCC_DBOX_1	226:234	Mutation altering degron motif	0.5647

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons