DegronMD - Q9NVH2(INTS7)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E876Q	TCGA-5L-AAT1	BRCA	TCGA	VEPHND	LIG_APCC_ABBA_1	881:886	Mutation rewiring degron network	0.1944
p.Q891R	TCGA-D1-A167	UCEC	TCGA	VEPHND	LIG_APCC_ABBA_1	881:886	Mutation rewiring degron network	0.1944
p.I896V	DO49095	COAD	ICGC	VEPHND	LIG_APCC_ABBA_1	881:886	Mutation rewiring degron network	0.0556
p.L879I	DO229022	LICA	ICGC	VEPHND	LIG_APCC_ABBA_1	881:886	Mutation rewiring degron network	0.2778
p.L873V	DO23246	LINC	ICGC	VEPHND	LIG_APCC_ABBA_1	881:886	Mutation rewiring degron network	0.1111
p.V890M	DO50803	LIRI	ICGC	VEPHND	LIG_APCC_ABBA_1	881:886	Mutation rewiring degron network	0.2222
p.A893V	DO51407	PRAD	ICGC	VEPHND	LIG_APCC_ABBA_1	881:886	Mutation rewiring degron network	0.1389
p.L879F	DO229446	SKCA	ICGC	VEPHND	LIG_APCC_ABBA_1	881:886	Mutation rewiring degron network	0.2778
p.Q871R	DO40978	UCEC	ICGC	VEPHND	LIG_APCC_ABBA_1	881:886	Mutation rewiring degron network	0.0556
p.E887K	DO43186	UCEC	ICGC	VEPHND	LIG_APCC_ABBA_1	881:886	Mutation rewiring degron network	0.3056
p.H882R	SNU-1040	large intestine	COSMIC	VEPHND	LIG_APCC_ABBA_1	881:886	Mutation altering degron motif	0.8244
p.T887K	D-336MG	central nervous system	COSMIC	VEPHND	LIG_APCC_ABBA_1	881:886	Mutation rewiring degron network	0.3056
p.H888R	SNU-1040	large intestine	COSMIC	VEPHND	LIG_APCC_ABBA_1	881:886	Mutation rewiring degron network	0.2778
p.T881K	D-336MG	central nervous system	COSMIC	VEPHND	LIG_APCC_ABBA_1	881:886	Mutation altering degron motif	0.7306

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons