DegronMD - Q9NWS0(PIH1D1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A197T	TCGA-78-7539	LUAD	TCGA	DLYTPAP	CBL_PTK	192:198	Mutation altering degron motif	0.6028
p.A197T	DO234239	ESAD	ICGC	DLYTPAP	CBL_PTK	192:198	Mutation altering degron motif	0.6028
p.A197T	DO26210	LUAD	ICGC	DLYTPAP	CBL_PTK	192:198	Mutation altering degron motif	0.6028
p.R186Q	DO229327	BTCA	ICGC	DLYTPAP	CBL_PTK	192:198	Mutation rewiring degron network	0.1667
p.P185S	DO234403	ESAD	ICGC	DLYTPAP	CBL_PTK	192:198	Mutation rewiring degron network	0.1389
p.P196T	DO228985	LICA	ICGC	DLYTPAP	CBL_PTK	192:198	Mutation altering degron motif	0.5919
p.P196T	DO229008	LICA	ICGC	DLYTPAP	CBL_PTK	192:198	Mutation altering degron motif	0.5919
p.P185L	DO228624	PRAD	ICGC	DLYTPAP	CBL_PTK	192:198	Mutation rewiring degron network	0.1389
p.S203A	SIDM01113	Other Sarcomas	GDSC	DLYTPAP	CBL_PTK	192:198	Mutation rewiring degron network	0.1944
p.S203A	ACH-000939	Sarcoma	CCLE	DLYTPAP	CBL_PTK	192:198	Mutation rewiring degron network	0.1944
p.S203A	SK-UT-1	soft tissue	COSMIC	DLYTPAP	CBL_PTK	192:198	Mutation rewiring degron network	0.1944
p.L190P	SIDM00214	Colorectal Carcinoma	GDSC	DLYTPAP	CBL_PTK	192:198	Mutation rewiring degron network	0.2778
p.L190P	ACH-000955	Colon/Colorectal Cancer	CCLE	DLYTPAP	CBL_PTK	192:198	Mutation rewiring degron network	0.2778
p.L190P	SNU-407	large intestine	COSMIC	DLYTPAP	CBL_PTK	192:198	Mutation rewiring degron network	0.2778
p.A197V	SIDM01451	Pancreatic Carcinoma	GDSC	DLYTPAP	CBL_PTK	192:198	Mutation altering degron motif	0.5825
p.A197V	ACH-000933	Pancreatic Cancer	CCLE	DLYTPAP	CBL_PTK	192:198	Mutation altering degron motif	0.5825

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons