DegronMD - Q9NWW0(HCFC1R1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P83L	TCGA-CQ-6229	HNSC	TCGA	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation rewiring degron network	0.1389
p.E61Q	TCGA-DK-A1A6	BLCA	TCGA	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation rewiring degron network	0.0556
p.E61Q	DO472	BLCA	ICGC	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation rewiring degron network	0.0556
p.P85R	DO10044	COAD	ICGC	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation rewiring degron network	0.0833
p.I70V	DO234183	ESAD	ICGC	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation rewiring degron network	0.3056
p.R75S	DO228948	LICA	ICGC	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation altering degron motif	0.7427
p.P85T	DO228948	LICA	ICGC	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation rewiring degron network	0.0833
p.P85T	DO229028	LICA	ICGC	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation rewiring degron network	0.0833
p.P85T	DO229009	LICA	ICGC	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation rewiring degron network	0.0833
p.P85T	NCI-H2023	lung	COSMIC	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation rewiring degron network	0.0833
p.P85H	DO228974	LICA	ICGC	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation rewiring degron network	0.0833
p.A73D	DO229045	LICA	ICGC	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation altering degron motif	0.7793
p.E72D	DO228904	LICA	ICGC	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation altering degron motif	0.6758
p.F66L	ACH-001610	Brain Cancer	CCLE	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation rewiring degron network	0.1944
p.A63T	ACH-002026	Endometrial/Uterine Cancer	CCLE	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation rewiring degron network	0.1111
p.L76V	A431	skin	COSMIC	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation altering degron motif	0.6765
p.P85S	Hs633T	soft tissue	COSMIC	LSLHND	LIG_APCC_ABBA_1	71:76	Mutation rewiring degron network	0.0833

Kaplan plot for HCFC1R1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

HCFC1R1

UniProt ID: Q9NWW0

Entrez ID: 54985

Protein name: Host cell factor C1 regulator 1 (HCF-1 beta-propeller-interacting protein)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for HCFC1R1 in