DegronMD - Q9NWZ5(UCKL1)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R77H	TCGA-AX-A1CE	UCEC	TCGA	PPWY	ITCH	85:88	Mutation rewiring degron network	0.1111
p.R77H	TCGA-DF-A2KU	UCEC	TCGA	PPWY	ITCH	85:88	Mutation rewiring degron network	0.1111
p.Y88H	TCGA-BG-A222	UCEC	TCGA	PPWY	ITCH	85:88	Mutation altering degron motif	0.7229
p.I79M	TCGA-BR-8690	STAD	TCGA	PPWY	ITCH	85:88	Mutation rewiring degron network	0.1667
p.I79M	TCGA-IN-A6RL	STAD	TCGA	PPWY	ITCH	85:88	Mutation rewiring degron network	0.1667
p.I79M	DO51738	STAD	ICGC	PPWY	ITCH	85:88	Mutation rewiring degron network	0.1667
p.I79M	DO47911	STAD	ICGC	PPWY	ITCH	85:88	Mutation rewiring degron network	0.1667
p.R84Q	TCGA-DU-5847	LGG	TCGA	PPWY	ITCH	85:88	Mutation rewiring degron network	0.3056
p.G92S	TCGA-IQ-A61E	HNSC	TCGA	PPWY	ITCH	85:88	Mutation rewiring degron network	0.2222
p.G92S	DO44429	HNSC	ICGC	PPWY	ITCH	85:88	Mutation rewiring degron network	0.2222
p.T78I	TCGA-W5-AA2I	CHOL	TCGA	PPWY	ITCH	85:88	Mutation rewiring degron network	0.1389
p.A82T	TCGA-ZF-A9R4	BLCA	TCGA	PPWY	ITCH	85:88	Mutation rewiring degron network	0.25
p.A82T	DO219061	BLCA	ICGC	PPWY	ITCH	85:88	Mutation rewiring degron network	0.25
p.G87S	DO222953	BTCA	ICGC	PPWY	ITCH	85:88	Mutation altering degron motif	0.6993
p.G95R	DO233116	GACA	ICGC	PPWY	ITCH	85:88	Mutation blocking phosphorylation signal	0.5833
p.T97N	DO32596	OV	ICGC	PPWY	ITCH	85:88	Mutation rewiring degron network	0.0833
p.A85V	DO51795	STAD	ICGC	PPWY	ITCH	85:88	Mutation altering degron motif	0.6936
p.S92I	DO42312	UCEC	ICGC	PPWY	ITCH	85:88	Mutation rewiring degron network	0.2222
p.E75G	ACH-001061	Colon/Colorectal Cancer	CCLE	PPWY	ITCH	85:88	Mutation rewiring degron network	0.0556
p.A85T	ACH-001518	Endometrial/Uterine Cancer	CCLE	PPWY	ITCH	85:88	Mutation altering degron motif	0.7139

Kaplan plot for UCKL1 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

UCKL1

UniProt ID: Q9NWZ5

Entrez ID: 54963

Protein name: Uridine-cytidine kinase-like 1 (EC 2.7.1.48)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for UCKL1 in