DegronMD - Q9NXB0(MKS1)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E3K	TCGA-LL-A6FP	BRCA	TCGA	STDTGE	DEG_Kelch_Keap1_1	7:12	Mutation rewiring degron network	0.2222
p.E3K	DO51212	BRCA	ICGC	STDTGE	DEG_Kelch_Keap1_1	7:12	Mutation rewiring degron network	0.2222
p.T4N	DO229018	LICA	ICGC	STDTGE	DEG_Kelch_Keap1_1	7:12	Mutation rewiring degron network	0.25
p.D19E	DO229036	LICA	ICGC	STDTGE	DEG_Kelch_Keap1_1	7:12	Mutation rewiring degron network	0.1389
p.R16S	DO229035	LICA	ICGC	STDTGE	DEG_Kelch_Keap1_1	7:12	Mutation rewiring degron network	0.2222
p.W6C	ACH-000599	Pancreatic Cancer	CCLE	STDTGE	DEG_Kelch_Keap1_1	7:12	Mutation rewiring degron network	0.3056
p.V21M	ACH-000994	Endometrial/Uterine Cancer	CCLE	STDTGE	DEG_Kelch_Keap1_1	7:12	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons