DegronMD - Q9NY57(STK32B)

STK32B

UniProt ID: Q9NY57

Entrez ID: 55351

Protein name: Serine/threonine-protein kinase 32B (EC 2.7.11.1) (Yet another novel kinase 2)

External links: UniprotKB HGNC RefSeq COSMIC

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GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V11M	TCGA-DF-A2KU	UCEC	TCGA	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation altering degron motif	0.6097
p.V11M	DO223286	UCEC	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation altering degron motif	0.6097
p.G3W	TCGA-MN-A4N5	LUAD	TCGA	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation substituting flanking lysine	0.3056
p.G3W	DO45332	LUAD	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation substituting flanking lysine	0.3056
p.A3V	DO230346	COCA	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation substituting flanking lysine	0.3056
p.E24K	DO234344	ESAD	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.0556
p.R23W	DO16077	HNSC	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.0833
p.R23W	DO47933	STAD	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.0833
p.F22L	DO22205	LGG	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.1111
p.E17D	DO229037	LICA	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.25
p.A3S	DO229041	LICA	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation substituting flanking lysine	0.3056
p.M7T	DO50973	LICA	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.3056
p.V21D	DO44915	LIHC	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.1389
p.P10R	DO23342	LINC	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation altering degron motif	0.6401
p.R23L	DO23586	LUAD	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.0833
p.R19Q	DO43306	UCEC	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.1944
p.R19Q	DO41379	UCEC	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.1944
p.E14K	DO41572	UCEC	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation altering degron motif	0.7022
p.R15M	DO41572	UCEC	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.3056
p.Q10H	DO41903	UCEC	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation altering degron motif	0.7582
p.R19W	DO43907	UCEC	ICGC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.1944
p.F20I	SIDM00941	Kidney Carcinoma	GDSC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.1667
p.F20I	ACH-000433	Kidney Cancer	CCLE	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.1667
p.F20I	CAKI-1	kidney	COSMIC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation rewiring degron network	0.1667
p.G3R	SIDM00901	Endometrial Carcinoma	GDSC	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation substituting flanking lysine	0.3056
p.G3R	ACH-000940	Endometrial/Uterine Cancer	CCLE	KPPVFDE	LIG_APCC_ABBAyCdc20_2	8:14	Mutation substituting flanking lysine	0.3056

Kaplan plot for STK32B in

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*NOTE: the Kaplan plots were collected from OncoLnc