DegronMD - Q9NYK6(EURL)

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GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S224L	TCGA-A6-2686	COAD	TCGA	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	TCGA-AJ-A3EL	UCEC	TCGA	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	TCGA-AP-A1DV	UCEC	TCGA	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	TCGA-AX-A0J0	UCEC	TCGA	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	TCGA-B5-A3FC	UCEC	TCGA	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	TCGA-D1-A3DH	UCEC	TCGA	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	TCGA-E6-A1LX	UCEC	TCGA	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	TCGA-EO-A22X	UCEC	TCGA	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	TCGA-EY-A1GI	UCEC	TCGA	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	DO7828	COAD	ICGC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	DO8898	COAD	ICGC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	DO222798	COCA	ICGC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	DO36881	READ	ICGC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	DO43482	UCEC	ICGC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	DO41020	UCEC	ICGC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	DO43186	UCEC	ICGC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	DO41542	UCEC	ICGC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	DO41871	UCEC	ICGC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	DO43907	UCEC	ICGC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	DO41211	UCEC	ICGC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	DO41133	UCEC	ICGC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	SIDM01288	Colorectal Carcinoma	GDSC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	SIDM00878	Breast Carcinoma	GDSC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	SIDM00954	Breast Carcinoma	GDSC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	SIDM00534	Colorectal Carcinoma	GDSC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	SIDM00118	Colorectal Carcinoma	GDSC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	SIDM01588	Endometrial Carcinoma	GDSC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	ACH-000930	Breast Cancer	CCLE	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	ACH-000986	Colon/Colorectal Cancer	CCLE	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	ACH-000993	Endometrial/Uterine Cancer	CCLE	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	ACH-001081	Colon/Colorectal Cancer	CCLE	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.S224L	ACH-001820	Breast Cancer	CCLE	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6556
p.T226S	DO228848	LICA	ICGC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.6005
p.Q213K	DO229031	LICA	ICGC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.1944
p.A235V	SIDM00217	Colorectal Carcinoma	GDSC	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.0833
p.A235V	ACH-000999	Colon/Colorectal Cancer	CCLE	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation rewiring degron network	0.0833
p.E220D	ACH-001520	Leukemia	CCLE	SREELNSMT	DEG_APCC_DBOX_1	218:226	Mutation altering degron motif	0.5647

DegronMD: protein-targeted degradation, mutation and drug response to degrons

EURL

UniProt ID: Q9NYK6

Entrez ID: 54149

Protein name: Protein EURL homolog

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for EURL in