DegronMD - Q9NZ09(UBAP1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A348V	TCGA-66-2768	LUSC	TCGA	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.0556
p.A345S	TCGA-AX-A06F	UCEC	TCGA	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.1389
p.L330M	TCGA-L5-A43J	ESCA	TCGA	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.2222
p.D327G	DO8264	COAD	ICGC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.1389
p.S344T	DO234180	ESAD	ICGC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.1667
p.S347C	DO26404	LUAD	ICGC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.0833
p.S344C	DO23786	LUAD	ICGC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.1667
p.S344C	DO45349	LUAD	ICGC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.1667
p.E331K	DO223286	UCEC	ICGC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.25
p.A345V	SIDM00845	Burkitt's Lymphoma	GDSC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.1389
p.A345V	Daudi	haematopoietic and lymphoid tissue	COSMIC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.1389
p.I327M	SIDM00898	Breast Carcinoma	GDSC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.1389
p.I327M	AU565	breast	COSMIC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.1389
p.L335P	SIDM00567	Other Solid Cancers	GDSC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation altering degron motif	0.6471
p.L335P	ONS-76	central nervous system	COSMIC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation altering degron motif	0.6471
p.N326S	SIDM00989	Bladder Carcinoma	GDSC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.1111
p.N326S	BFTC-905	urinary tract	COSMIC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.1111
p.N341K	SIDM01772	Mesothelioma	GDSC	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.25
p.Q339K	ACH-000571	Brain Cancer	CCLE	ALTSS	DEG_SPOP_SBC_1	334:338	Mutation rewiring degron network	0.3056

Kaplan plot for UBAP1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

UBAP1

UniProt ID: Q9NZ09

Entrez ID: 51271

Protein name: Ubiquitin-associated protein 1 (UBAP-1) (Nasopharyngeal carcinoma-associated gene 20 protein)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for UBAP1 in