DegronMD - Q9NZU7(CABP1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E118K	DO51612	CESC	ICGC	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation rewiring degron network	0.1667
p.A114V	DO230342	COCA	ICGC	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation rewiring degron network	0.2778
p.E98Q	DO14566	HNSC	ICGC	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation blocking phosphorylation signal	0.5556
p.T108K	DO27357	LUSC	ICGC	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation altering degron motif	0.7306
p.R118Q	DO222405	MELA	ICGC	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation rewiring degron network	0.1667
p.G121R	DO222423	MELA	ICGC	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation rewiring degron network	0.0833
p.G121R	DO37425	SKCM	ICGC	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation rewiring degron network	0.0833
p.M121I	ACH-000707	Lymphoma	CCLE	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation rewiring degron network	0.0833
p.P118S	ACH-000925	Lung Cancer	CCLE	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation rewiring degron network	0.1667
p.R112C	ACH-000953	Leukemia	CCLE	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation altering degron motif	0.8301
p.R112C	SUP-T1	haematopoietic and lymphoid tissue	COSMIC	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation altering degron motif	0.8301
p.E110K	Hs939-T	skin	COSMIC	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation altering degron motif	0.7022
p.M121L	PF-382	haematopoietic and lymphoid tissue	COSMIC	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation rewiring degron network	0.0833
p.P122L	H2591	pleura	COSMIC	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation rewiring degron network	0.0556
p.A117V	MFE-319	endometrium	COSMIC	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation rewiring degron network	0.1944
p.V106M	SW684	soft tissue	COSMIC	PATPQSS	DEG_SCF_FBW7_1	106:112	Mutation altering degron motif	0.7208

Kaplan plot for CABP1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CABP1

UniProt ID: Q9NZU7

Entrez ID: 9478

Protein name: Calcium-binding protein 1 (CaBP1) (Calbrain) (Caldendrin)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CABP1 in