RELCH
UniProt ID: Q9P260
Entrez ID: 57614
Protein name: RAB11-binding protein RELCH (LisH domain and HEAT repeat-containing protein KIAA1468) (RAB11 binding and LisH domain, coiled-coil and HEAT repeat-containing) (RAB11-binding protein containing LisH, coiled-coil, and HEAT repeats)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Regulates intracellular cholesterol distribution from recycling endosomes to the trans-Golgi network through interactions with RAB11 and OSBP (PubMed:29514919). Functions in membrane tethering and promotes OSBP-mediated cholesterol transfer between RAB11-bound recycling endosomes and OSBP-...
FUNCTION: Regulates intracellular cholesterol distribution from recycling endosomes to the trans-Golgi network through interactions with RAB11 and OSBP (PubMed:29514919). Functions in membrane tethering and promotes OSBP-mediated cholesterol transfer between RAB11-bound recycling endosomes and OSBP-bound Golgi-like membranes (PubMed:29514919). {ECO:0000269|PubMed:29514919}.
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GO - Biological processes (BP):
intracellular cholesterol transport [GO:0032367]...
intracellular cholesterol transport [GO:0032367]
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GO - Molecular function (MF):
...
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GO - Cellular component (CC):
recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]...
recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]
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RELCH
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*NOTE: the Kaplan plots were collected from OncoLnc