DegronMD - Q9P266(JCAD)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V341G	SIDM01960	Colorectal Carcinoma	GDSC	PPVY	ITCH	337:340	Mutation rewiring degron network	0.3056
p.V341G	SIDM01960	Colorectal Carcinoma	GDSC	PPSY	ITCH	343:346	Mutation rewiring degron network	0.2778
p.V341A	SIDM01169	Ovarian Carcinoma	GDSC	PPVY	ITCH	337:340	Mutation rewiring degron network	0.3056
p.V341A	SIDM01169	Ovarian Carcinoma	GDSC	PPSY	ITCH	343:346	Mutation rewiring degron network	0.2778
p.V341A	TOV-21G	ovary	COSMIC	PPVY	ITCH	337:340	Mutation rewiring degron network	0.3056
p.V341A	TOV-21G	ovary	COSMIC	PPSY	ITCH	343:346	Mutation rewiring degron network	0.2778
p.R305M	SIDM00746	Non-Small Cell Lung Carcinoma	GDSC	PPSY	ITCH	295:298	Mutation rewiring degron network	0.1389
p.R305M	NCI-H1648	lung	COSMIC	PPSY	ITCH	295:298	Mutation rewiring degron network	0.1389
p.T1185R	SIDM00937	Oral Cavity Carcinoma	GDSC	VVTST	DEG_SPOP_SBC_1	1181:1185	Mutation altering degron motif	0.7876
p.T1185R	CAL-27	upper aerodigestive tract	COSMIC	VVTST	DEG_SPOP_SBC_1	1181:1185	Mutation altering degron motif	0.7876

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons