DegronMD - Q9P2E2(KIF17)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D511N	TCGA-06-5416	GBM	TCGA	VFSTT	DEG_SPOP_SBC_1	500:504	Mutation rewiring degron network	0.1389
p.D511N	TCGA-3B-A9HT	SARC	TCGA	VFSTT	DEG_SPOP_SBC_1	500:504	Mutation rewiring degron network	0.1389
p.D511N	TCGA-FI-A2D5	UCEC	TCGA	VFSTT	DEG_SPOP_SBC_1	500:504	Mutation rewiring degron network	0.1389
p.D511N	DO10880	GBM	ICGC	VFSTT	DEG_SPOP_SBC_1	500:504	Mutation rewiring degron network	0.1389
p.D511N	DO219934	SARC	ICGC	VFSTT	DEG_SPOP_SBC_1	500:504	Mutation rewiring degron network	0.1389
p.D511N	DO41331	UCEC	ICGC	VFSTT	DEG_SPOP_SBC_1	500:504	Mutation rewiring degron network	0.1389
p.S513F	TCGA-44-2659	LUAD	TCGA	VFSTT	DEG_SPOP_SBC_1	500:504	Mutation rewiring degron network	0.0833
p.S513F	DO23744	LUAD	ICGC	VFSTT	DEG_SPOP_SBC_1	500:504	Mutation rewiring degron network	0.0833
p.V495E	TCGA-44-5644	LUAD	TCGA	VFSTT	DEG_SPOP_SBC_1	500:504	Mutation rewiring degron network	0.1944
p.V495E	DO25153	LUAD	ICGC	VFSTT	DEG_SPOP_SBC_1	500:504	Mutation rewiring degron network	0.1944
p.T503M	DO233772	GACA	ICGC	VFSTT	DEG_SPOP_SBC_1	500:504	Mutation altering degron motif	0.7423
p.K499N	DO232224	PBCA	ICGC	VFSTT	DEG_SPOP_SBC_1	500:504	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons