DegronMD - Q9P2W1(PSMC3IP)

PSMC3IP

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A138T	TCGA-AX-A1CE	UCEC	TCGA	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation rewiring degron network	0.2778
p.A138T	TCGA-EO-A22U	UCEC	TCGA	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation rewiring degron network	0.2778
p.H153R	TCGA-DU-6392	LGG	TCGA	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation rewiring degron network	0.1944
p.E142Q	TCGA-HQ-A5NE	BLCA	TCGA	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation altering degron motif	0.5633
p.G140A	DO224662	BRCA	ICGC	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation altering degron motif	0.754
p.T143M	DO223732	CESC	ICGC	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation altering degron motif	0.7423
p.T143M	DO48016	STAD	ICGC	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation altering degron motif	0.7423
p.T143M	IST-SL1	lung	COSMIC	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation altering degron motif	0.7423
p.N148T	DO220201	SARC	ICGC	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation altering degron motif	0.7055
p.V149I	DO38495	STAD	ICGC	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation rewiring degron network	0.3056
p.V149I	DO47717	STAD	ICGC	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation rewiring degron network	0.3056
p.V149I	DO43306	UCEC	ICGC	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation rewiring degron network	0.3056
p.V149I	SUP-T1	haematopoietic and lymphoid tissue	COSMIC	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation rewiring degron network	0.3056
p.K133Q	DO39016	THCA	ICGC	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation rewiring degron network	0.1389
p.F136C	DO52412	UCEC	ICGC	YRERLKNIK	DEG_APCC_DBOX_1	140:148	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc