DegronMD - Q9UBG0(MRC2)

MRC2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A674S	TCGA-21-1077	LUSC	TCGA	PDPTPSLT	DEG_SCF_FBW7_1	659:666	Mutation rewiring degron network	0.1111
p.A674S	DO26725	LUSC	ICGC	PDPTPSLT	DEG_SCF_FBW7_1	659:666	Mutation rewiring degron network	0.1111
p.P657L	TCGA-BH-A0E6	BRCA	TCGA	PDPTPSLT	DEG_SCF_FBW7_1	659:666	Mutation rewiring degron network	0.2778
p.P657L	DO5668	BRCA	ICGC	PDPTPSLT	DEG_SCF_FBW7_1	659:666	Mutation rewiring degron network	0.2778
p.P661S	TCGA-FW-A3R5	SKCM	TCGA	PDPTPSLT	DEG_SCF_FBW7_1	659:666	Mutation altering degron motif	0.5641
p.P661S	DO37406	SKCM	ICGC	PDPTPSLT	DEG_SCF_FBW7_1	659:666	Mutation altering degron motif	0.5641
p.D676Y	DO229015	LICA	ICGC	PDPTPSLT	DEG_SCF_FBW7_1	659:666	Mutation rewiring degron network	0.0556
p.S668F	DO222875	MELA	ICGC	PDPTPSLT	DEG_SCF_FBW7_1	659:666	Mutation rewiring degron network	0.2778
p.S664R	DO229275	THCA	ICGC	PDPTPSLT	DEG_SCF_FBW7_1	659:666	Mutation altering degron motif	0.6316
p.P670R	ACH-001673	Bile Duct Cancer	CCLE	PDPTPSLT	DEG_SCF_FBW7_1	659:666	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc